Numerical Simulation of Conduction Delay in Blocked Purkinje Tissue
نویسندگان
چکیده
منابع مشابه
Numerical simulation of conduction delay in blocked Purkinje tissue.
The model used for passive conduction in muscle fibers consisted of a region of nonpropagating fiber of variable length, bounded proximally and distally by normal active tissue. The voltage variation on this fiber was governed by the passive wave equation. This system was analyzed by Fourier series techniques on the digital computer, using a cardiac action potential as the input. With a fixed d...
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Characterization of concentration- and use-dependent effects of quinidine from conduction delay and declining conduction velocity in canine Purkinje fibers.
The dynamic response of squared conduction velocity, theta 2, to repetitive stimulation in canine Purkinje fibers with quinidine was studied using a double-microelectrode technique. With stimulation, a frequency-dependent monoexponential increase in conduction delay (CD) and a decline in theta 2 were observed. The exponential rates and changes in steady-state CD and theta 2 were frequency- and ...
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We have studied in vitro preparations of canine right and left papillary muscles to determine the excitation sequences of the Purkinje and ventricular cells, using both monopolar surface electrodes and intracellular microelectrodes. Our results show, for right papillary muscles, that the Purkinje layer covers the basal part of the muscle, and that activation from the right bundle branch propaga...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1972
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.31.1.53